Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online:121
  • Home
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2020  |  Volume : 5  |  Issue : 1  |  Page : 17-21

Precious platelets: The utility of cold-stored and cryopreserved platelets


1 Department of Clinical Haematology and BMT, Tata Medical Center, Kolkata, West Bengal, India
2 Molecular Genetics, Guys Hospital/Kings College London, London, United Kingdom
3 Department of Respiratory Medicine at William Harvey Hospital, Ashford, United Kingdom

Correspondence Address:
Rizwan Javed
Department of Clinical Haematology and BMT, Tata Medical Center, Kolkata, West Bengal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/GJTM.GJTM_19_20

Rights and Permissions

The current storage temperature of platelets prepared by both pooled buffy coats and by apheresis is 22°C + 2°C (room temperature [RT]). The adverse microbiological and metabolic implications associated with RT storage have restricted the shelf life of platelets from 5 to 7 days. The proposed alternative is cold-stored (4°C) platelets that could be stored for 21 days and cryopreserved platelets with dimethyl sulfoxide for up to 2 years at −80°C. An increase in shelf life could be of great utility in rural and military settings. Based on the proven quality and properties of cold-stored platelets, the US Food and Drug Authority has approved its use for up to 3 days in patients having active bleeding.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed841    
    Printed78    
    Emailed0    
    PDF Downloaded40    
    Comments [Add]    

Recommend this journal