Global Journal of Transfusion Medicine

SPECIAL COMMUNICATION
Year
: 2019  |  Volume : 4  |  Issue : 1  |  Page : 126--127

Retrospectrive analysis of Rh(D) negative patients needing emergency rescue transfusion using “matched transfusions”


Liang Jing, Yang Li-Ping, Liu Wen, Liu Jing-Han, Lan Jiong-Cai 
 The Sixth Subsidiary Hospital of Xingjiang Medical University, Urumqi 830002, Xinjiang, China

Correspondence Address:
Dr. Lan Jiong-Cai
The Sixth Subsidiary Hospital of Xingjiang Medical University, Urumqi 830002, Xinjiang
China
Dr. Liu Jing-Han
The Sixth Subsidiary Hospital of Xingjiang Medical University, Urumqi 830002, Xinjiang
China




How to cite this article:
Jing L, Li-Ping Y, Wen L, Jing-Han L, Jiong-Cai L. Retrospectrive analysis of Rh(D) negative patients needing emergency rescue transfusion using “matched transfusions”.Glob J Transfus Med 2019;4:126-127


How to cite this URL:
Jing L, Li-Ping Y, Wen L, Jing-Han L, Jiong-Cai L. Retrospectrive analysis of Rh(D) negative patients needing emergency rescue transfusion using “matched transfusions”. Glob J Transfus Med [serial online] 2019 [cited 2019 Dec 15 ];4:126-127
Available from: http://www.gjtmonline.com/text.asp?2019/4/1/126/256752


Full Text



 Introduction



In China, Rh(D)-negative rate is relatively lower, so there are fewer Rh(D)-negative blood donors, and there is not sufficient Rh(D)-negative blood. Therefore, the difficulty of blood supply for Rh(D)-negative patients lies not only in the rarity of this blood type but also its availability at times of emergency. For critically ill emergency patients with massive hemorrhage, it takes a lot of time for procuring, thawing and washing of Rh(D) negative frozen units leading to difficulties in rescuing and treating patients with massive haemorrhage. In January 2014, Blood Transfusion Physician Branch and Clinical Transfusion Branch of Chinese Medical Association published special circumstance and emergency rescue transfusion recommendation and provided an operable plan for transfusion treatment of emergency patients in special circumstances.

Objective

This is a retrospective analysis of Rh(D) Negative patients who were rescued with Rh(D) Positive transfusions till Rh(D) Negative cells were available. This study explores the safety and efficacy of this combined transfusion.

 Methods



We compared the effectiveness of 6 matched blood transfusion (case group) with 6 same type blood transfusion (control group) in Xinjiang' Aksu area from January 2014 to December 2015, to explore matched blood transfusion's safety and effectiveness. The effectiveness indexes include patients' basic information, red cell antibody screening, total bilirubin, concentration of hemoglobin (Hb), reticulocyte count, hematocrit, and hospitalization days.

 Results



The case group and the control group were analyzed from transfusion safety index and curative effect assessment index [Table 1] and [Table 2]. Seventy-two hours after transfusion, erythrocyte antibody was negative, and there was no anti-D; the actual rising values of Hb at 24 h after transfusion were 28.53 ± 10.09 g/L and 21.24 ± 3.13 g/L; there were no complications of noninfectious transfusion. The difference between the case group and the control group before and after transfusion had no statistical significance [Table 1].{Table 1}{Table 2}

 Conclusions



Application of “matched blood transfusion” in special and emergency situations for Rh(D) Negative patients is a safe and effective clinical transfusion treatment. A formal tracking, follow-up, and assessment system should be established for patients needing blood transfusion of Rh(D)-positive red blood cells. Rh(D)-negative red blood cell transfusion should be the first choice for Rh(D)-negative patients, and those who need emergency rescue transfusion can receive “matched blood transfusion” following regular procedures.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.