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Year : 2020  |  Volume : 5  |  Issue : 1  |  Page : 17-21

Precious platelets: The utility of cold-stored and cryopreserved platelets

1 Department of Clinical Haematology and BMT, Tata Medical Center, Kolkata, West Bengal, India
2 Molecular Genetics, Guys Hospital/Kings College London, London, United Kingdom
3 Department of Respiratory Medicine at William Harvey Hospital, Ashford, United Kingdom

Correspondence Address:
Rizwan Javed
Department of Clinical Haematology and BMT, Tata Medical Center, Kolkata, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/GJTM.GJTM_19_20

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The current storage temperature of platelets prepared by both pooled buffy coats and by apheresis is 22°C + 2°C (room temperature [RT]). The adverse microbiological and metabolic implications associated with RT storage have restricted the shelf life of platelets from 5 to 7 days. The proposed alternative is cold-stored (4°C) platelets that could be stored for 21 days and cryopreserved platelets with dimethyl sulfoxide for up to 2 years at −80°C. An increase in shelf life could be of great utility in rural and military settings. Based on the proven quality and properties of cold-stored platelets, the US Food and Drug Authority has approved its use for up to 3 days in patients having active bleeding.

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