Global Journal of Transfusion Medicine

REVIEW ARTICLE
Year
: 2020  |  Volume : 5  |  Issue : 1  |  Page : 17--21

Precious platelets: The utility of cold-stored and cryopreserved platelets


Rizwan Javed1, Frozan Ahmadi2, Asheer Jawed3 
1 Department of Clinical Haematology and BMT, Tata Medical Center, Kolkata, West Bengal, India
2 Molecular Genetics, Guys Hospital/Kings College London, London, United Kingdom
3 Department of Respiratory Medicine at William Harvey Hospital, Ashford, United Kingdom

Correspondence Address:
Rizwan Javed
Department of Clinical Haematology and BMT, Tata Medical Center, Kolkata, West Bengal
India

The current storage temperature of platelets prepared by both pooled buffy coats and by apheresis is 22°C + 2°C (room temperature [RT]). The adverse microbiological and metabolic implications associated with RT storage have restricted the shelf life of platelets from 5 to 7 days. The proposed alternative is cold-stored (4°C) platelets that could be stored for 21 days and cryopreserved platelets with dimethyl sulfoxide for up to 2 years at −80°C. An increase in shelf life could be of great utility in rural and military settings. Based on the proven quality and properties of cold-stored platelets, the US Food and Drug Authority has approved its use for up to 3 days in patients having active bleeding.


How to cite this article:
Javed R, Ahmadi F, Jawed A. Precious platelets: The utility of cold-stored and cryopreserved platelets.Glob J Transfus Med 2020;5:17-21


How to cite this URL:
Javed R, Ahmadi F, Jawed A. Precious platelets: The utility of cold-stored and cryopreserved platelets. Glob J Transfus Med [serial online] 2020 [cited 2021 Sep 22 ];5:17-21
Available from: https://www.gjtmonline.com/article.asp?issn=2468-8398;year=2020;volume=5;issue=1;spage=17;epage=21;aulast=Javed;type=0